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GRADED CASES

Clinical scenarios

Pick a case, choose your airway strategy, ventilate to target and get a graded debrief on your decisions.

Ventilator for this case

Difficulty
Acuity
invasive
Severedifficult

Obesity Hypoventilation — Failed Home BiPAP, Hypercapnic Stupor

42-year-old woman with obesity hypoventilation syndrome, found unresponsive at home on her own bilevel machine after two days of increasing sleepiness. Slow snoring respirations, CO2 near 90 — the machine is not keeping up.

TeachesIn the massively obese patient, size the breath to predicted body weight, ramp the position, and use real PEEP — volumes sized to actual weight blow plateau pressures past safe limits.

Special population

The patient the case was written around.

mixed
Criticaldifficult

COPD Exacerbation — BiPAP Failing Mid-Transport

69-year-old man with COPD placed on BiPAP after a two-day exacerbation. Ten minutes into transport he becomes drowsy, his rate falls, and the CO2 climbs — BiPAP is failing.

TeachesBiPAP is a trial with an exit plan. A falling respiratory rate with a rising CO2 in a drowsy COPD patient is fatigue, not improvement — intubate before the arrest, not after.

Special population

The patient the case was written around.

invasive
Severemoderate

Circuit Disconnect — Sudden Low-Pressure Alarm in Transport

54-year-old man, post-ROSC and intubated, stable on the ventilator for five minutes of transport — until the circuit pulls away at the ET adapter and the low-pressure alarm sounds.

TeachesA low-pressure alarm is a circuit problem until proven otherwise. Bag the patient first, then troubleshoot from the tube outward — the patient should never wait for the machine.

Special population

The patient the case was written around.

invasive
Severemoderate

ALS — Failing Bellows, Falling Vital Capacity at Home

61-year-old man with three years of ALS, now unable to cough after a choking episode at breakfast. Shallow paradoxical breathing and a CO2 in the sixties — the bellows are failing while the lungs are still normal.

TeachesIn neuromuscular failure the lungs are normal but the pump is gone — the ventilator must do all the work. And succinylcholine is forbidden: chronic denervation means fatal hyperkalemia.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Severe Asthma in Pregnancy — Third Trimester RSI

28-year-old woman, 31 weeks pregnant, three days of worsening asthma that has stopped responding to everything. Tripoding, speaking single words, silent chest — she needs a tube with two patients in mind.

TeachesIn late pregnancy the chest is stiff, the oxygen reservoir is small, and there are two patients on the tube. Pre-oxygenate perfectly, keep the pressure capped, and hold the EtCO2 low enough to protect uterine blood flow.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Cuff Leak — Falling Exhaled Volume in Transport

66-year-old woman, intubated for severe pneumonia and stable in transport, until the exhaled volume alarm trips and a wet leak is heard at the mouth with every breath.

TeachesFalling exhaled volume with an audible leak is a cuff or tube problem, not a lung problem. Check the pilot balloon, add air, and confirm the volumes match — be ready to exchange the tube if the leak will not seal.

Special population

The patient the case was written around.

invasive
Severedifficult

Smoke Inhalation — Airway Burn at the Fire Scene

38-year-old carried out of a house fire with facial burns, soot around the mouth and hoarseness progressing to stridor on scene.

TeachesAn airway burn closes from above: secure the tube early, then ventilate the chemical injury underneath like ARDS.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Post-ROSC — Prolonged Arrest, Ongoing Resuscitation

58-year-old man in refractory ventricular fibrillation, intubated during ongoing resuscitation, with ROSC achieved after the fourth shock.

TeachesAfter a long arrest, hold a normal CO2 and avoid both too little and too much oxygen.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Tension Pneumothorax — After Intubation in a Collision

33-year-old driver intubated after a head-on collision who becomes suddenly impossible to ventilate minutes into the transport.

TeachesThe first minutes of positive pressure can create a tension — recognize the pattern early and decompress.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Drowning — Cold-Water Submersion, Profound Hypoxemia

24-year-old pulled from a cold lake after a prolonged submersion, profoundly hypoxemic with copious pink froth in the airway.

TeachesDrowning behaves like ARDS from the first minute: the surfactant is washed out, and PEEP is what reopens the lung.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Hypovolemic Shock — Pelvic Fracture, No Blood Products

26-year-old motorcyclist with an open pelvic fracture, profoundly hypotensive and tachycardic, with only crystalloid available.

TeachesLow preload with normal lungs: keep the pressures minimal and treat the shock with volume, not with the ventilator.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Anaphylaxis — Refractory, Surgical Airway Threat

45-year-old woman with angioedema of the tongue and lips after a shellfish meal, whose stridor is worsening despite repeated epinephrine.

TeachesEpinephrine first, airway second — and the tube goes in before the swelling closes it.

Special population

The patient the case was written around.

invasive
Severedifficult

ARDS — Aspiration and Refractory Hypoxemia

48-year-old woman with aspiration pneumonitis after a drug overdose who has progressed to refractory hypoxemia despite escalating oxygen.

TeachesA stiff, flooded lung is managed with low volumes and enough PEEP — chasing a perfect saturation with pressure causes harm.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Hypovolemic Shock — Low Preload in Transport

A 41-year-old with a gunshot wound to the abdomen, profoundly hypotensive and tachycardic at the scene, now intubated and ventilated en route to the trauma center.

TeachesPositive pressure steals preload — in shock the ventilator can deepen the very hypotension it was meant to treat.

Special population

The patient the case was written around.

invasive
Severedifficult

Guillain-Barré — Rapidly Progressive, Ventilator Dependent

36-year-old man with rapidly ascending weakness who has lost the ability to cough, swallow or breathe adequately.

TeachesWhen the lungs are normal and the pump has failed, the patient needs full support — not a weaning mode.

Special population

The patient the case was written around.

invasive
Severedifficult

Flail Chest — Trapped Driver

34-year-old restrained driver trapped in a high-speed MVC. Paradoxical chest wall movement on the right with severe pain and hypoxia at the roadside.

TeachesA broken chest wall wants low volumes and low pressures — the ventilator can turn a rib fracture into a tension pneumothorax.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Status Asthmaticus — Ventilated in the Field, Sky-High Pressures

27-year-old woman in status asthmaticus, intubated on scene after a silent chest and exhaustion. Airway pressures are extremely high on the first breaths in the truck.

TeachesIn severe obstruction, control the pressure and accept a high CO2 — a normal CO2 bought with a tensioned chest kills.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Massive Pulmonary Embolism — Field Presentation

55-year-old collapsed at an airport gate after a long-haul flight. Sudden dyspnea, presyncope and a saturation of 82% on room air, now profoundly hypotensive.

TeachesWhen the lungs sound clear but the blood is blocked, a low EtCO2 means dead space, not hypoventilation — more rate will not fix it.

Special population

The patient the case was written around.

invasive
Severedifficult

COPD — Severe Exacerbation Requiring Intubation

71-year-old man with a severe COPD exacerbation who has failed non-invasive support and is now barely rousable.

TeachesIn a chronic retainer the CO2 target is their own baseline, not 40 — and a slow rate is what lets the lung empty.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Tension Pneumothorax — Decompress in the Field

A 24-year-old motorcyclist, helmet ejected, GCS 7 at the roadside. You intubate on scene and the peak pressure jumps on the first breaths in the back of the truck.

TeachesA sudden rise in pressure with a falling blood pressure is a needle problem, not a ventilator problem.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Status Asthmaticus — Adult, Silent Chest

22-year-old man in a severe asthma attack at a bus stop, now with minimal air movement and a silent chest.

TeachesA silent chest means almost no air is moving — the quietest asthma is the most dangerous. Slow the rate and let the breath out.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Massive PE — Collapsed at a Bus Terminal

62-year-old woman who collapsed at a bus terminal with sudden dyspnea and presyncope, now profoundly hypotensive with a low EtCO2.

TeachesA failing right ventricle cannot tolerate pressure inside the chest — keep PEEP and tidal volumes low.

Special population

The patient the case was written around.

invasive
Severemoderate

Guillain-Barré — Ascending Weakness at Home

41-year-old whose family called 911 after three days of ascending weakness, now unable to lift their head off the pillow and with a weak, ineffective cough.

TeachesA falling vital capacity, not a falling saturation, is what signals the need for ventilation.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Pulmonary Contusion — Motorcycle Versus Car

29-year-old motorcyclist thrown over the handlebars, with a bruised and tender left chest and worsening hypoxemia.

TeachesA normal saturation on scene does not mean a normal lung — contusion declares itself later.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Sepsis — Abdominal Source, Normal Lungs

71-year-old man with abdominal pain and fever, now confused, tachypneic and acidotic, with clear lungs and a normal saturation.

TeachesNormal lungs with high CO2 production — a low EtCO2 here can mean low cardiac output rather than good ventilation.

Special population

The patient the case was written around.

invasive
Criticaldifficult

Post-ROSC — Ventilation During Transport

49-year-old woman in cardiac arrest with ROSC after three shocks, now intubated in the back of the truck en route to a tertiary center.

TeachesAfter ROSC the brain is vulnerable to both too little and too much oxygen — hold a normal CO2 and wean the oxygen down.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Aspiration — Overdose and Emesis

37-year-old found unresponsive after a mixed overdose, who vomited and aspirated before the crew arrived.

TeachesProtect the airway first, then ventilate a chemically injured lung.

Special population

The patient the case was written around.

invasive
Severemoderate

Severe Head Injury — Blown Pupil and Rising ICP

34-year-old man after an MVC with a severe head injury. GCS 6 at the roadside, requiring airway protection and controlled ventilation.

TeachesA blown pupil means herniation — brief hyperventilation buys time while the cause is treated.

Special population

The patient the case was written around.

mixed
Mildeasy

Free Practice — Normal Lungs

A stable, ventilated adult in the back of the truck with normal lung mechanics and no clinical target.

TeachesA normal lung is the baseline — learn what each setting does to pressure, flow and volume before anything goes wrong.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Aspiration — Post-ictal Vomiting

44-year-old found seizing at home, now post-ictal and hypoxemic after vomiting, with gastric contents suctioned from the airway on scene.

TeachesAspiration injures the lung from the inside — expect it to behave like a stiff, shunting lung.

Special population

The patient the case was written around.

noninvasive
Moderatemoderate

Asthma — Fatiguing After Two Days of Wheeze

33-year-old man with two days of worsening wheeze, now tiring with a rising CO2 despite continuous nebulizers.

TeachesFatigue is the warning sign: a tiring asthmatic needs pressure control and time to exhale.

Special population

The patient the case was written around.

invasive
Mildeasy

Opioid Overdose — Slumped Behind the Wheel

35-year-old found slumped behind the wheel at a red light by a passer-by, with pinpoint pupils, blue lips and a respiratory rate of 5.

TeachesA slow rate with a rising CO2 is hypoventilation — count the breaths before you reach for the ventilator.

Special population

The patient the case was written around.

invasive
Severemoderate

Drowning — Post-immersion Hypoxemia

19-year-old pulled from a lake after four minutes of submersion. GCS 5, copious frothy secretions, and profound hypoxemia immediately after intubation on the shoreline.

TeachesAfter a submersion the hypoxemia outlasts the event — PEEP keeps the flooded units open.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Neuromuscular Weakness — Myasthenic Crisis

68-year-old woman with known myasthenia gravis, now unable to swallow her secretions or lift her head off the pillow.

TeachesA failing pump with normal lungs needs full support and close attention to secretions.

Special population

The patient the case was written around.

invasive
Severedifficult

Severe Pneumonia — ARDS Physiology in Transport

55-year-old man with pneumonia progressing to ARDS physiology. Bilateral infiltrates, refractory hypoxemia and a P/F ratio of 120, now being transported to a tertiary center.

TeachesARDS physiology on a transport: low volumes, adequate PEEP, and a plateau pressure that stays under 30.

Special population

The patient the case was written around.

invasive
Mildeasy

Opioid Overdose — Hypoventilation in the Field

28-year-old found unresponsive in a park with pinpoint pupils and a respiratory rate of 6 after a suspected heroin overdose. Naloxone has been given, but ventilation remains inadequate.

TeachesThe lungs are healthy and the drive to breathe is gone — support the rate and volume, and give the antidote.

Special population

The patient the case was written around.

noninvasive
Mildeasy

COPD — Home Oxygen and Morning Drowsiness

74-year-old man with severe COPD found drowsy in his armchair by his daughter, with a saturation of 96% on his home oxygen at 4 L/min.

TeachesIn a chronic retainer, oxygen is titrated to 88–92% — too much of it can blunt the drive to breathe.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Pneumonia — Septic Hypoxemia in a Care Home

72-year-old in a nursing facility with fever, productive cough and progressive dyspnea. SpO2 84% on a non-rebreather, tachypneic with accessory muscle use.

TeachesSepsis raises CO2 production and shunts blood past the lung — the numbers move for two reasons at once.

Special population

The patient the case was written around.

invasive
Severemoderate

Anaphylaxis — Airway Swelling and Bronchospasm

32-year-old stung by a bee at a park, now with urticaria, an audible wheeze and a hoarse, stridulous voice that is getting quieter.

TeachesTwo problems at once: an airway closing above and bronchospasm below.

Special population

The patient the case was written around.

noninvasive
Moderatemoderate

Pulmonary Edema — Hypertensive Crisis at a Wedding

66-year-old man who became acutely breathless at a wedding reception, now sitting bolt upright, drenched in sweat, with a blood pressure of 214/118.

TeachesThe heart is the problem — positive pressure buys time while the afterload comes down.

Special population

The patient the case was written around.

invasive
Mildeasy

Post-ictal Hypoventilation — No Aspiration

51-year-old man who had a generalized seizure at home and is now post-ictal and breathing shallowly, with no evidence of aspiration.

TeachesA sedated patient who has stopped breathing needs support until the drive comes back.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Pulmonary Contusion — Extrication and Transport

34-year-old unrestrained driver extricated from a high-speed collision. Bilateral lower-zone opacities and worsening hypoxemia in the back of the truck despite a high-flow mask.

TeachesA contused lung stiffens over hours — reassess the pressures as the case goes on.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Pneumonia — Influenza Season, Rapid Deterioration

63-year-old woman with three days of fever and myalgia who has deteriorated rapidly in the last two hours with bilateral infiltrates.

TeachesDeterioration within minutes in a case that looked stable — reassess the patient, not the settings.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Head Injury — Cushing's Response and Impending Herniation

57-year-old man found on the pavement after a ground-level fall, smelling of alcohol, with a head laceration and a GCS of 7.

TeachesCushing's response — high blood pressure with a slow pulse — is a late sign of rising pressure inside the skull.

Special population

The patient the case was written around.

invasive
Mildeasy

Post-operative Hypoventilation — Splinting After Surgery

62-year-old man on the second day after an open laparotomy, now drowsy and hypoxemic with shallow, splinted breathing.

TeachesPain splints the chest — the fix is analgesia plus support, not a bigger tidal volume.

Special population

The patient the case was written around.

noninvasive
Severemoderate

COPD Exacerbation — Severe, Tiring on Scene

68-year-old man with known COPD, increasing dyspnea and wheezing over the past day, found by a neighbor. Too breathless to speak in full sentences.

TeachesA tiring COPD patient on bilevel needs the pressures titrated against the CO2 — and a plan for when it fails.

Special population

The patient the case was written around.

noninvasive
Severemoderate

Acute Pulmonary Edema — CPAP in the Field

78-year-old woman with acute decompensated heart failure, frothy sputum and orthopnea, found in bed struggling to breathe.

TeachesCPAP opens the flooded alveoli and reduces the work of breathing — watch for the blood pressure falling.

Special population

The patient the case was written around.

noninvasive
Moderatemoderate

COPD — Nursing Home, Declining Intubation

79-year-old woman in a care home with an acute COPD exacerbation who has a signed order declining intubation.

TeachesThe right answer can be non-invasive support and a ceiling of care — not every case ends with a tube.

Special population

The patient the case was written around.

invasive
Moderatemoderate

Smoke Inhalation — Apartment Fire, Early

46-year-old man pulled from a smoke-filled apartment, coughing soot-stained sputum with singed nasal hairs.

TeachesEarly stridor after a fire means the airway is closing, and carbon monoxide hides behind a normal saturation.

Special population

The patient the case was written around.

noninvasive
Mildeasy

COPD Exacerbation — Bilevel Support at Home

68-year-old with known COPD, two days of worsening breathlessness and a productive cough. The family called 911. Alert, sitting forward in a chair and using accessory muscles.

TeachesBilevel support offloads the work of breathing and often keeps a COPD patient off a tube altogether.

Special population

The patient the case was written around.

invasive
Mildeasy

Head Injury — Intubated for Airway Protection

31-year-old man who fell from a ladder, with a head injury and a GCS of 8. Intubated on scene for airway protection, now in the truck.

TeachesA head injury wants a normal CO2 — hyperventilating a brain with normal pressure causes ischemia for no gain.

Special population

The patient the case was written around.

invasive
Mildeasy

Nursing Home Pneumonia — Early Hypoxemia

81-year-old resident of a care home with a two-day history of fever and a wet cough, now hypoxemic and mildly confused.

TeachesA low tidal volume per predicted body weight protects the lung even when the case looks straightforward.

Special population

The patient the case was written around.

noninvasive
Mildeasy

Pulmonary Edema — Missed Dialysis

58-year-old woman on hemodialysis who missed two sessions, now breathless at rest with bilateral crackles and a blood pressure of 188/104.

TeachesFluid in the alveoli is opened up with PEEP, and the same positive pressure unloads the heart.

Special population

The patient the case was written around.

invasive
Mildeasy

Anaphylaxis — Wasp Sting at a Barbecue

40-year-old woman stung by a wasp at a barbecue, now with urticaria, vomiting and a wheeze that has developed over ten minutes.

TeachesEpinephrine is the treatment; the ventilator only supports the bronchospasm underneath it.

Special population

The patient the case was written around.

noninvasive
Mildeasy

Asthma Exacerbation — Not Improving With Nebulizers

26-year-old woman with known asthma, wheezing heavily after two days of a cold, not improving after three nebulizers.

TeachesGive the breath time to leave the chest — rate and inspiratory time matter as much as the drug.

Special population

The patient the case was written around.

noninvasive
Moderatemoderate

Obesity Hypoventilation — Home Bilevel Support

58-year-old with a BMI of 52, daytime somnolence and morning headaches, found drowsy with shallow breathing and CO2 retention during a chest infection.

TeachesA heavy chest wall needs a higher inspiratory pressure, and the target is the patient's own baseline CO2.

Special population

The patient the case was written around.

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