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VENT ESSENTIALS

Vent Essentials

Everything you need to keep a patient alive and get them to the hospital — nothing else. The Basics is the four decisions, four settings and five numbers. The Protocol tab is the same thing as a flow chart: one box, one decision, read top to bottom.

Ventilation targets, starting settings and drug doses vary between services and are set by your medical director. This page is a general approach, not an order set — follow your own service protocol and online medical control, and where the two disagree, your protocol wins.

The whole job, in four moves

In this order. If you are reading nothing else on this page, read this.

  1. 1
    Bag first, think second

    If they are not breathing, or not breathing enough, put a bag-valve-mask on their face and squeeze. Two hands, good seal, one breath every 5 to 6 seconds. Nothing you do on the ventilator matters until this is working.

  2. 2
    Decide: tube, or no tube

    Tube them if they cannot protect their own airway, are not breathing on their own, or are failing BiPAP or CPAP. If they are awake, talking and moving air, try BiPAP first. If you are not sure — keep bagging and ask for help.

  3. 3
    Pick one mode and set four numbers

    Assist-control volume control (A/C-VC). Then tidal volume, rate, PEEP and FiO2. Leave every other knob exactly where the machine put it.

  4. 4
    Watch two numbers, not twelve

    SpO2 is about oxygen: turn FiO2 up or down. EtCO2 is about breathing: turn the rate up or down. Those two cover almost everything you will actually have to fix.

If you remember nothing else

  • Bag if in doubt — it always buys you time.
  • 6 mL/kg predicted body weight.
  • Rate 16. PEEP 5.
  • FiO2 to keep SpO2 at 92 – 96%.
  • When they crash, DOPE — and bag while you work it out.

What to set on a normal adult

Assist-control volume control, and four numbers. Change nothing else until these are right.

ModeA/C-VC

Every breath is the size you set, at the rate you set. The patient can still trigger extra breaths on top of that.

Tidal volume6 mL/kg

Of predicted body weight — from height and sex, never the stretcher weight. For an average adult that is about 350 to 450 mL. Big breaths tear lungs.

Rate16 /min

16 to 20 is fine. Do not crank it up to catch up — blowing off too much CO2 drops the blood pressure.

PEEP5 cmH2O

Keeps the small air sacs from collapsing between breaths. Raise it only if the saturation will not hold on oxygen alone.

FiO2100% → wean

Start at 100%, then come down to the lowest number that keeps SpO2 at 92 to 96%. Never leave it at 100% just in case.

Everything elseLeave it

I:E 1:2, flow around 50 L/min, trigger −2. The defaults are what you want.

Tidal volume already worked out

HeightMaleFemale
5'0"300 mL270 mL
5'4"360 mL330 mL
5'8"410 mL380 mL
6'0"470 mL440 mL
6'4"520 mL490 mL

Predicted body weight from height and sex, then 6 mL/kg. A child is dosed the same way from a weight chart — never from what the patient actually weighs.

Starting settings and tidal volume targets vary by service and by patient. Check them against the protocol you carry before you dial them in.

The numbers worth watching

Five, and only the first two will send you to a knob.

SpO292 – 96%

Oxygen in the blood. A COPD patient at risk of retaining CO2 is held at 88 to 92% — enough oxygen, without pushing the CO2 up.

EtCO235 – 45 mmHg

Breathing, measured at the airway. With a head injury keep it 35 to 40 — a high CO2 raises the pressure inside the skull.

Peak pressureunder 40

The pressure it takes to push each breath in. Above 40, something is blocking the way — go to DOPE.

Plateau pressureunder 30

The pressure actually stretching the air sacs. Over 30 and you are injuring the lung.

Blood pressuresystolic over 90

Positive pressure squeezes the heart. If the pressure falls as you raise PEEP, that patient needs fluid — not a higher PEEP.

Which knob to turn

Two variables: oxygen for the saturation, rate for the CO2. Small steps, then look at the patient again.

SpO2 below targetFiO2 up

Turn oxygen up in steps. If 100% still will not hold it, the problem is the tube or the chest, not the oxygen.

SpO2 above targetFiO2 down

Wean in steps to the lowest FiO2 that holds the saturation — 21% if that is what it takes. Oxygen is a drug with a dose, and the wean costs nothing.

EtCO2 over 45Rate up 2

Slow or shallow breathing is the usual reason the CO2 is climbing.

EtCO2 under 35Rate down 2

You are blowing off more CO2 than the patient is making.

Peak pressure over 40Stop and DOPE

Do not turn anything up. Find out what is blocking the breath first.

Blood pressure fallingFluid, and no more PEEP

Volume first. A dry patient cannot carry the pressure you are giving them.

They are getting worse right now

The first move is always the same: take them off the ventilator and bag. It costs nothing, and it tells you whether the problem is the machine or the patient. Then work DOPE.

DDisplacement

Look at the depth marking at the teeth and listen to both sides of the chest. If the tube moved, it is in the wrong place.

OObstruction

Suction the tube. Mucus, blood or a kink is the most common cause of a pressure that suddenly climbs.

PPneumothorax

One side with no air moving, and the blood pressure falling. Put a needle in that chest.

EEquipment

Take them off the ventilator and bag. If they get better on the bag, the machine was the problem.

Needle decompression, tube troubleshooting and when to escalate are set by your service. Follow the protocol and the procedures you are credentialed for, and call medical control early.

What the alarms mean

In plain words, and what to do about each one.

HIGH PRESSUREA blocked breath

Tube, chest, or the patient coughing. Work DOPE.

LOW PRESSURE / LOW VOLUMEA leak or a disconnect

Follow the circuit from the machine to the face and find the gap.

LOW SpO2Not enough oxygen

Turn FiO2 up first, then check the tube — in that order, because oxygen is free and fast.

APNEANo spontaneous effort

The patient has stopped triggering. In a spontaneous mode — CPAP or pressure support — the machine will not breathe for them: bag, and switch to a mode with a set rate.

LOW MINUTE VOLUMENot enough air moving

Look for a leak first, then the rate.

The mistakes that hurt people

None of these are rare. All of them are avoidable.

  • Ventilating too big. 6 mL/kg, not 10. Over-sized breaths are the injury the whole low-tidal-volume literature exists to prevent.
  • Ventilating too fast. It drives the CO2 down, which drops the blood pressure and cuts blood flow to the brain.
  • Chasing a perfect number while the patient gets worse. Treat the patient, not the screen.
  • Blaming the machine before checking the tube. It is nearly always the tube.
  • Leaving FiO2 at 100% because it feels safe. Wean it down.
  • Raising PEEP on a patient who is dry. Pressure without volume is how a ventilated patient arrests.

Try it before you need it

Run a normal patient on the simulator and turn these four knobs until the numbers land where they should. No score, no case — just the machine and the patient.

Where these numbers come from

Every number on this page is a published one. These are the sources it was checked against.

When you have time to learn it properly

Four real destinations, not homepages. Start with the ICU OnePager if you only open one.

For training & education only — not for patient care. Protocols vary: follow your own service protocol and medical direction.ContactPrivacy PolicyTerms of Use
© 2026 Joseph D. Silver. App design, interface, simulation engine and case library — all rights reserved. Education content is credited to its published sources; ventilator names and designs belong to their manufacturers.Contact: josephdsilver44@gmail.com